Take2 Prophecy™ Test for Nasopharyngeal Cancer (NPC)


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  • By the world-class research team from The Chinese University of Hong Kong 
  • The test utilities the NGS technology invented 
  • Sensitivity greater than 97%
  • Simple and non-invasive, only requires a single blood draw


Take2 Prophecy™ Test for Nasopharyngeal Cancer (NPC) (with Doctor Consultation)

Take2 Prophecy™️ Test for Nasopharyngeal Cancer is a ground-breaking, blood-based, and non-invasive early cancer detection test. It analyses human and NPC-associated genomic signatures of EBV DNA in the blood plasma using a combination of Polymerase Chain Reaction (PCR) and Next-generation Sequencing (NGS) technologies. It enables NPC patients to be identified in their early stage for timely treatment and increases their survival rate.


  • Sensitivity greater than 97%
  • The test utillises the NGS technology invented
  • The world-class research team from The Chinese University of Hong Kong
  • Simple and non-invasive, only requires a single blood draw
  • The results ready in 3-7 working days
  • Doctor Consultation



What is NPC?
Nasopharyngeal cancer (NPC) is a type of head and neck cancer which originates in the nasopharynx. The nasopharynx is located at the “concealed” area between the middle of the head, at the end of the nasal cavity, and the upper part of the throat.

NPC is also named the “Guangdong cancer”!
NPC, also known as “Guangdong cancer”, has a particularly high incidence rate in Southeast Asia and Southern China, especially in Guangdong and Guangxi provinces and Hong Kong. In Hong Kong, NPC is one of the top ten cancers, and there are 600-800 new cases every year. It is also one of the top five cancers for men aged between 45-64 in the past ten years.

As the symptoms of early NPC resemble flu or inflammatory illnesses (refer to the graph below), it is usually hard for patients to relate the symptoms to NPC at the early stage, causing a delay in seeking medical intervention. Research shows that 80% of unscreened patients were diagnosed with NPC at a late stage.

Are you able to protect yourself against NPC without a vaccine?
The symptoms of NPC at an early stage are non-specific and not easy to be identified. There is no vaccine to prevent and no specific medication to cure NPC. Early detection is the key to make a difference.

With the launch of our pioneering technologies, NPC patients can be identified at the early stage, which enables timely treatment. NPC patients might have less treatment side effects and better survival. The survival rate of early-stage NPC patients could be higher than 90%.


Symptoms of NPC:

  • Partial headache
  • Hearing loss
  • Blood-stained nasal discharge
  • Swallowing difficulty 
  • Hoarse voice
  • Neck swelling

Risk Factors of NPC:

  • Smoking
  • Having a diet rich in salt-cured food
  • Infection with Epstein-Barr Virus (EBV)
  • Frequent exposure to formaldehyde or chemicals
  • Frequent exposure to other carcinogens
  • Family history


Name or description of the test Take2 Prophecy™ Test for Nasopharyngeal Cancer Traditional EBV DNA test Traditional EBV serology tests
Technology PCR and NGS PCR only Enzyme-linked immunosorbent assay (ELISA)
Detection target Human and NPC-associated genomic signatures of EBV DNA EBV DNA Antibody of EBV (eg: IgA-VCA)
False positive rate 0.7% around 3.4% up to 40%
Sensitivity >97% around 81.4% 42.9-92.7%
Validated for early NPC detection with large-scale clinical trial


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