Description

PanBRCA™ Inherited Breast & Ovarian Cancer Screening Test

PanBRCA™ (OBS) : $8,160

PanBRCA™ (OBF) : $15,600

 

Breast cancer is the third most deadly cancer among women in Hong Kong, second only to lung cancer and colorectal cancer. In recent years, many studies have found that mutations in BRCA1&2 genes are related to various cancers. The occurrence of pathogenic mutations in BRCA genes will lead to the failure of the DNA repair mechanism and increase the risk of cancers. If there is an inherited mutation in genes, the chance of rapid cell division and change increases, and the possibility of developing cancer is also greater.

 

• In 2019, a total of 852 women died from this cancer in Hong Kong, accounting for 13.7% of all cancer deaths in females
• It is estimated that more than 5 million people in China carry BRCA disease-causing gene mutations
• In Asians, the risk of a cancer-causing mutation in the BRCA gene represent as below: 87% of Breast cancer
• 44% of ovarian cancer and also an increased risk for other types of cancer (such as pancreatic cancer, colorectal cancer, prostate cancer, etc.)

 

Specifically Designed for Asians – Common Asian – Specific Gene Mutations

• Using next-generation sequencing (NGS) and the most advanced technology to detect any genetic mutations, including gene rearrangements and large deletions of BRCA1&2 genes, related to hereditary breast cancer and ovarian cancer
• Designed for screening Asian genetic mutations, with coverage up to 95%

 

High Accuracy Trustworthy Bioinformatics

• PanBRCA™ uses advanced data analysis technology to achieve a higher detection and analytical sensitivity than most other BRCA test in the market
• A confirmatory test will be performed in dual to ensure the highest accuracy
• The test is highly rated with exceptional performance in the Proficiency testing program provided by the College of American Pathologist (CAP)

 

PanBRCA™ Screening Test Features

	Other Tests (HRM)	PanBRCA™ (OBS)	PanBRCA™ (OBF)
Price	–	$8,160	$15,600
BRCA genes Mutation Coverage %	73-90%	Up to 90-95%	Up to 99.9%
Turnaround time (TAT)	Irregular	Within 14-20working days
Superiority	–	Golden Standard & Comprehensive Coverage

 

Test Specifications

Test Code	Methodology	Specimen Requirements
OBS	NGS (Next Generation Sequencing)	6ml of EDTA blood / 10 Buccal Swabs
OBF	NGS + Multiplex ligation-dependent probe amplification (MLPA)

 

PanBRCA™ Screening Test

• Collect samples by drawing 6ml of EDTA blood or 10 buccal swabs
• Within 14-20 working days
• 100% Hong Kong laboratory, analysis and professional test report

 

Suitable for

• Early onset breast cancer (<45years old)
• Bilateral or multiple primary breast cancers
• Male breast cancer at any age
• Breast and ovarian cancer in the same women
• 3 or more cases of breast cancer in the family
• 3 or more cases of breast, ovarian and/or pancreatic cancer in the family
• 3 or more cases of breast, uterine and/or thyroid cancer in the family
• Multiple close family members with breast and other cancers

 

 

Instructions for use：

• Must be used on or before the expiration date
• Please show your confirmation information, order number, registered full name and phone number for verification

 

Terms and Conditions：

• This voucher is only valid for Trinity Medical Centre.
• The voucher must be paid on or before 30 June 2024, can be used at Central , Causeway Bay or Tsim Sha Tsui Trinity Medical Centre.
• This voucher must be used within 90 days after purchase and this voucher is not valid after expiration.
• This voucher is non-refundable and cannot be redeemed for full or partial cash.
• You must bring this ticket to the front desk when you register.
• This voucher cannot be used with any other special offers and promotions.
• If this voucher is lost or stolen, we will not accept any liability and will not provide any reissue in such case.
• If you have any questions, please call 2192 7022 or email tmc@trinitymedical.com.hk
• Trinity Medical Centre reserves the right to amend the above Terms and Conditions without prior notice. In case of any disputes, Trinity Medical Centre reserves all rights for final decision.