{"id":70703,"date":"2025-09-09T13:59:47","date_gmt":"2025-09-09T05:59:47","guid":{"rendered":"https:\/\/trinitymedical.com.hk\/product\/panhered\/"},"modified":"2026-04-09T09:56:44","modified_gmt":"2026-04-09T01:56:44","slug":"panhered_bg","status":"publish","type":"product","link":"https:\/\/trinitymedical.com.hk\/cn\/product\/panhered_bg\/","title":{"rendered":"PanHERED\u2122 \u9057\u4f20\u6027\u4e73\u764c\u548c\u5987\u79d1\u764c\u75c7\u57fa\u56e0\u6d4b\u8bd5\u7ec4\u5408"},"content":{"rendered":"<p>\u4fdd\u62a4\u60a8\u7684\u5065\u5eb7\uff0c\u4ece\u9057\u4f20\u68c0\u6d4b\u5f00\u59cb\uff01 PanHERED\u2122 \u9057\u4f20\u6027\u4e73\u764c\u548c\u5987\u79d1\u764c\u75c7\u7ec4\u5408\u68c0\u6d4b\u662f\u4e13\u4e3a\u5973\u6027\u5065\u5eb7\u8bbe\u8ba1\u3002\u65e0\u8bba\u60a8\u662f\u5426\u6709\u5bb6\u65cf\u764c\u75c7\u53f2\uff0c\u8fd9\u9879\u68c0\u6d4b\u90fd\u80fd\u5e2e\u52a9\u60a8\u53ca\u65e9\u4e86\u89e3\u9057\u4f20\u98ce\u9669\uff0c\u5b9e\u73b0\u9884\u9632\u80dc\u4e8e\u6cbb\u7597\u7684\u7406\u5ff5\uff0c\u8ba9\u60a8\u548c\u5bb6\u4eba\u5b89\u5fc3\u9762\u5bf9\u672a\u6765\u3002<\/p>\n<hr \/>\n<h2>\u4e3a\u4f55\u9057\u4f20\u6027\u4e73\u764c\u548c\u5987\u79d1\u764c\u75c7\u57fa\u56e0\u6d4b\u8bd5\u91cd\u8981\uff1f<\/h2>\n<p>\u9057\u4f20\u6027\u764c\u75c7\u901a\u5e38\u4e0e\u7279\u5b9a\u57fa\u56e0\u7a81\u53d8\u76f8\u5173\uff0c\u8fd9\u4e9b\u7a81\u53d8\u53ef\u80fd\u5728\u5bb6\u65cf\u4e2d\u4f20\u9012\u3002\u5982\u679c\u60a8\u643a\u5e26\u67d0\u4e9b\u9ad8\u98ce\u9669\u57fa\u56e0\u7a81\u53d8\uff0c\u7f79\u60a3\u4e73\u764c\u6216\u5176\u4ed6\u5987\u79d1\u764c\u75c7\u7684\u673a\u7387\u5c06\u663e\u8457\u589e\u52a0\u3002\u4f8b\u5982\uff1a<\/p>\n<ul>\n<li>BRCA1\u7a81\u53d8\uff1a\u53ef\u5c06\u4e73\u764c\u7ec8\u751f\u98ce\u9669\u63d0\u9ad8\u81f355-65%<\/li>\n<li>BRCA2\u7a81\u53d8\uff1a\u4e73\u764c\u7ec8\u751f\u98ce\u9669\u7ea6\u4e3a45-47%<\/li>\n<\/ul>\n<h2>\u9057\u4f20\u6027\u57fa\u56e0\u68c0\u6d4b\u4e0d\u6b62\u4e8eBRCA1 &amp; 2\uff1f<\/h2>\n<p>\u5728\u9057\u4f20\u6027\u4e73\u764c\u4e0e\u5375\u5de2\u764c\u7684\u9884\u9632\u4e2d\uff0c\u8bb8\u591a\u4eba\u9996\u5148\u60f3\u5230\u7684\u662fBRCA1\u4e0eBRCA2\u57fa\u56e0\u68c0\u6d4b\uff0c\u56e0\u4e3a\u8fd9\u4e9b\u57fa\u56e0\u7a81\u53d8\u4f1a\u663e\u8457\u589e\u52a0\u4e73\u764c\uff0855-65%\u7ec8\u751f\u98ce\u9669\uff09\u548c\u5375\u5de2\u764c\u7684\u53d1\u751f\u673a\u7387\u3002\u7136\u800c\uff0c\u73b0\u4ee3\u533b\u5b66\u7814\u7a76\u663e\u793a\uff0c\u57fa\u56e0\u68c0\u6d4b\u8fdc\u4e0d\u6b62\u4e8eBRCA1 &amp; 2\u3002\u900f\u8fc7\u591a\u57fa\u56e0\u9762\u677f\u6d4b\u8bd5\uff0c\u53ef\u4ee5\u6db5\u76d6\u66f4\u591a\u76f8\u5173\u57fa\u56e0\uff0c\u5e2e\u52a9\u8bc6\u522b\u66f4\u5e7f\u6cdb\u7684\u9057\u4f20\u98ce\u9669\uff0c\u4ece\u800c\u5b9e\u73b0\u66f4\u6709\u6548\u7684\u65e9\u671f\u9884\u9632\u548c\u4e2a\u4eba\u5316\u5065\u5eb7\u7ba1\u7406\u3002<\/p>\n<p>BRCA1\u4e0eBRCA2\u57fa\u56e0\u867d\u662f\u9057\u4f20\u6027\u4e73\u764c\u7684\u4e3b\u8981\u6210\u56e0\uff0c\u4f46\u5e76\u975e\u552f\u4e00\u3002\u7814\u7a76\u6307\u51fa\uff0c\u5176\u4ed6\u57fa\u56e0\u53d8\u5f02\u4e5f\u53ef\u589e\u52a0\u764c\u75c7\u98ce\u9669\uff0c\u4f8b\u5982TP53\u57fa\u56e0\u7a81\u53d8\u7684\u4e73\u764c\u7ec8\u751f\u98ce\u9669\u8fbe46-60%\uff0c\u6216CDH1\u768439-52%\u3002 <strong>\u5982\u679c\u4ec5\u68c0\u6d4bBRCA1\/2\uff0c\u53ef\u80fd\u9519\u8fc740-50%\u7684\u9057\u4f20\u6027\u764c\u75c7\u4e2a\u6848\u3002 <\/strong><\/p>\n<table style=\"border-collapse: collapse; width: 100%; font-family: Arial, sans-serif; border: 1px solid #dcdcdc; margin-bottom: 20px;\">\n<thead>\n<tr style=\"background-color: #ea668b; color: #ffffff; text-align: central;\">\n<th style=\"padding: 12px; border: 1px solid #dcdcdc;\">\u57fa\u56e0<\/th>\n<th style=\"padding: 12px; border: 1px solid #dcdcdc;\">\u60a3\u4e0a\u4e73\u764c\u98ce\u9669<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr style=\"background-color: #ffffff; text-align: central;\">\n<td style=\"padding: 12px; border: 1px solid #dcdcdc; text-align: center;\">BRCA1<\/td>\n<td style=\"padding: 12px; border: 1px solid #dcdcdc; text-align: center;\">55-65%<\/td>\n<\/tr>\n<tr style=\"background-color: #f9f9f9; text-align: central;\">\n<td style=\"padding: 12px; border: 1px solid #dcdcdc; text-align: center;\">BRCA2<\/td>\n<td style=\"padding: 12px; border: 1px solid #dcdcdc; text-align: center;\">45-47%<\/td>\n<\/tr>\n<tr style=\"background-color: #ffffff; text-align: central;\">\n<td style=\"padding: 12px; border: 1px solid #dcdcdc; text-align: center;\">TP53<\/td>\n<td style=\"padding: 12px; border: 1px solid #dcdcdc; text-align: center;\">49-60%<\/td>\n<\/tr>\n<tr style=\"background-color: #f9f9f9; text-align: central;\">\n<td style=\"padding: 12px; border: 1px solid #dcdcdc; text-align: center;\">PTEN<\/td>\n<td style=\"padding: 12px; border: 1px solid #dcdcdc; text-align: center;\">25-50%<\/td>\n<\/tr>\n<tr style=\"background-color: #ffffff; text-align: central;\">\n<td style=\"padding: 12px; border: 1px solid #dcdcdc; text-align: center;\">PALB2<\/td>\n<td style=\"padding: 12px; border: 1px solid #dcdcdc; text-align: center;\">33-58%<\/td>\n<\/tr>\n<tr style=\"background-color: #f9f9f9; text-align: central;\">\n<td style=\"padding: 12px; border: 1px solid #dcdcdc; text-align: center;\">STK11<\/td>\n<td style=\"padding: 12px; border: 1px solid #dcdcdc; text-align: center;\">30-50%<\/td>\n<\/tr>\n<tr style=\"background-color: #ffffff; text-align: central;\">\n<td style=\"padding: 12px; border: 1px solid #dcdcdc; text-align: center;\">CDH1<\/td>\n<td style=\"padding: 12px; border: 1px solid #dcdcdc; text-align: center;\">39-52%<\/td>\n<\/tr>\n<tr style=\"background-color: #f9f9f9; text-align: central;\">\n<td style=\"padding: 12px; border: 1px solid #dcdcdc; text-align: center;\">ATM<\/td>\n<td style=\"padding: 12px; border: 1px solid #dcdcdc; text-align: center;\">15-25%<\/td>\n<\/tr>\n<tr style=\"background-color: #ffffff; text-align: central;\">\n<td style=\"padding: 12px; border: 1px solid #dcdcdc; text-align: center;\">CHEK2<\/td>\n<td style=\"padding: 12px; border: 1px solid #dcdcdc; text-align: center;\">20-44%<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>*\u4e0a\u8ff0\u8d44\u6599\u6765\u6e90\u81eaPangenia &#8211; PanHERED\u2122 Hereditary Breast and Gynecologic Cancers Panel \u5ba3\u4f20\u518c<\/p>\n<hr \/>\n<h2>PanHERED\u2122 \u9057\u4f20\u6027\u4e73\u764c\u548c\u5987\u79d1\u764c\u75c7\u57fa\u56e0\u6d4b\u8bd5\u7ec4\u5408<\/h2>\n<p>\u4e3a\u9057\u4f20\u6027\u4e73\u764c\u4e0e\u5987\u79d1\u764c\u75c7\u7efc\u5408\u6d4b\u8bd5\u7ec4\u5408\uff0c\u6db5\u76d6 20 \u4e2a\u57fa\u56e0 (ATM, BARD1, BRCA1, BRCA2, BRIP1, CDH1, CHEK2, EPCAM, MLH1, MSH2, MSH6, NBN, NF1, PALB2, PMS2, PTEN, RAD51C, RAD51D, STK11, TP53)\uff0c\u5305\u62ec\u4e73\u764c\u3001\u5375\u5de2\u764c\u3001\u5b50\u5bab\u4f53\u764c\u7b49\u5987\u79d1\u764c\u75c7\u76f8\u5173\u57fa\u56e0\uff0c\u63d0\u4f9b\u66f4\u5e7f\u6cdb\u7684\u98ce\u9669\u8bc4\u4f30\u3002<\/p>\n<p>\u68c0\u6d4b\u9002\u77e5\u4eba\u58eb:<\/p>\n<ul>\n<li>\u6709\u4e73\u764c\u3001\u5375\u5de2\u764c\u3001\u5b50\u5bab\u4f53\u764c\u7b49\u5987\u79d1\u764c\u75c7\u5bb6\u65cf\u53f2\u8005<\/li>\n<li>\u5e74\u8f7b\u65f6\uff0845\u5c81\u4ee5\u4e0b\uff09\u786e\u8bca\u4e73\u764c\u6216\u5987\u79d1\u764c\u75c7\u8005<\/li>\n<li>\u540c\u65f6\u60a3\u6709\u4e73\u764c\u548c\u5375\u5de2\u764c\u6216\u5b50\u5bab\u4f53\u764c\u8005<\/li>\n<li>\u6709\u591a\u4f4d\u76f4\u7cfb\u4eb2\u5c5e\u66fe\u60a3\u4e73\u764c\u3001\u5375\u5de2\u764c\u6216\u5b50\u5bab\u4f53\u764c\u8005<\/li>\n<\/ul>\n<p>PanHERED\u2122 \u4e0d\u4ec5\u662f\u4e00\u9879\u57fa\u56e0\u68c0\u6d4b\uff0c\u66f4\u662f\u4e00\u9879\u5bf9\u60a8\u548c\u5bb6\u4eba\u5065\u5eb7\u7684\u957f\u671f\u6295\u8d44\u3002\u901a\u8fc7\u4e86\u89e3\u60a8\u7684\u9057\u4f20\u98ce\u9669\uff0c\u60a8\u53ef\u4ee5\u91c7\u53d6\u79ef\u6781\u7684\u9884\u9632\u63aa\u65bd\uff0c\u964d\u4f4e\u764c\u75c7\u53d1\u75c5\u98ce\u9669\uff0c\u5e76\u4e3a\u4e0b\u4e00\u4ee3\u6811\u7acb\u5065\u5eb7\u7684\u699c\u6837\u3002\u9009\u62e9PanHERED\u2122\uff0c\u8ba9\u5065\u5eb7\u4ece\u4e86\u89e3\u5f00\u59cb\uff0c\u8ba9\u5173\u7231\u5ef6\u7eed\u5230\u672a\u6765\u3002<\/p>\n<hr \/>\n<p><img fetchpriority=\"high\" decoding=\"async\" class=\"alignnone size-full wp-image-70695\" src=\"https:\/\/trinitymedical.com.hk\/wp-content\/uploads\/2025\/09\/202507-Pangenia-PanHERED-04.png\" alt=\"\" width=\"3183\" height=\"2250\" title=\"\"><\/p>\n<p>\u8d44\u6599\u6765\u6e90:<\/p>\n<ul>\n<li>\u9999\u6e2f\u9632\u764c\u4f1a\u7f51\u7ad9, \u6700\u65b0\u764c\u75c7\u7edf\u8ba1<\/li>\n<li>Hong Kong Medical Journal. A new paradigm of genetic testing for hereditary breast\/ovarian cancers<\/li>\n<li>The Genetics of Cancer. National Cancer Institute. U.S. Department of Health and Human Services<\/li>\n<li>\u764c\u75f4\u6027\u764c\u75c7 &#8211; \u53f0\u5927\u533b\u9662\u57fa\u56e0\u533b\u5b66\u90e8<\/li>\n<li>National Comprehensive Cancer Network<\/li>\n<\/ul>\n<hr \/>\n<p>\u5982\u4f55\u4f7f\u7528\uff1a<\/p>\n<ul>\n<li>\u9700\u5728\u6709\u6548\u671f\u6216\u4e4b\u524d\u5151\u6362<\/li>\n<li>\u8bf7\u51fa\u793a\u786e\u8ba4\u8d44\u8baf\u3001\u8ba2\u5355\u53f7\u3001\u767b\u8bb0\u5168\u540d\u548c\u7535\u8bdd\u53f7\u7801\u4ee5\u8fdb\u884c\u9a8c\u8bc1<\/li>\n<\/ul>\n<p><strong>\u9884\u7ea6\u6d41\u7a0b\u53ca\u6761\u6b3e\u7ec6\u5219\uff1a<\/strong><\/p>\n<ul>\n<li>\u5ba2\u6237\u4e8e\u5168\u4ec1\u533b\u52a1\u4e2d\u5fc3\u7f51\u5e97\u8d2d\u4e70\u57fa\u56e0\u68c0\u6d4b\u8ba1\u753b\u540e\uff0c\u5c06\u6536\u5230\u7531\u7f51\u5e97\u5bc4\u51fa\u7684\u6210\u529f\u4ed8\u6b3e\u7684\u786e\u8ba4\u7535\u90ae\u3002\u672c\u4e2d\u5fc3\u5c06\u4e8e\u968f\u540e\u7684\u529e\u516c\u65f6\u95f4\u5185\u81f4\u7535\u5ba2\u6237\uff0c\u5b89\u6392\u9884\u7ea6\u57fa\u56e0\u68c0\u6d4b\u7684\u65f6\u95f4\u53ca\u5730\u70b9\u3002\u5ba2\u6237\u4ea6\u53ef\u5728\u8ba2\u5355\u786e\u8ba4\u540e\uff0c\u81f4\u7535\u672c\u4e2d\u5fc3\uff08\u7535\u8bdd\uff1a2192 7022\uff09\u6216\u53d1\u9001\u7535\u90ae\u81f3 tmc@trinitymedical.com.hk \u9884\u7ea6\u3002 <\/li>\n<li>\u6b64\u8ba1\u5212\u53ea\u9650\u4e8e\u5168\u4ec1\u7f51\u5e97\u8d2d\u4e70\u53ca\u53ea\u9650\u4e8e\u6307\u5b9a\u5168\u4ec1\u533b\u52a1\u4e2d\u5fc3\u8fdb\u884c\u3002\u4e0d\u53ef\u4e0e\u5176\u4ed6\u4f18\u60e0\u5171\u540c\u4f7f\u7528\uff0c\u4ea6\u4e0d\u53ef\u8f6c\u8ba9\u4ed6\u4eba\u3001\u9000\u6b3e\uff0c\u6216\u5151\u6362\u6210\u5168\u90e8\u6216\u90e8\u5206\u73b0\u91d1\u3002 <\/li>\n<li>\u5ba2\u6237\u8d2d\u4e70\u65e5\u8d77 90 \u65e5\u5185\u9884\u7ea6\u53ca\u63a5\u53d7\u68c0\u6d4b\uff0c\u903e\u671f\u4f5c\u5e9f\u3002 <\/li>\n<li>\u5982\u786e\u8ba4\u7535\u90ae\u6216\u8ba2\u5355\u9057\u5931\u6216\u88ab\u76d7\uff0c\u6211\u4eec\u6055\u4e0d\u627f\u62c5\u4efb\u4f55\u8d23\u4efb\uff0c\u4ea6\u4e0d\u4f1a\u8865\u53d1\u4efb\u4f55\u786e\u8ba4\u7535\u90ae\u6216\u8ba2\u5355\u3002 <\/li>\n<li>\u5ba2\u6237\u5fc5\u987b\u4e8e\u672c\u4e2d\u5fc3\u767b\u8bb0\u65f6\uff0c\u51fa\u793a\u8eab\u5206\u8bc1\u660e\u6587\u4ef6\u53ca\u6210\u529f\u4ed8\u6b3e\u7684\u786e\u8ba4\u7535\u90ae\uff0c\u65b9\u53ef\u4eab\u7528\u670d\u52a1\u3002 <\/li>\n<li>\u5982\u5bb6\u957f\u6216\u76d1\u62a4\u4eba\u4e3a\u672a\u6210\u5e74\u5b50\u5973\u8d2d\u4e70\u670d\u52a1\uff0c\u670d\u52a1\u4f7f\u7528\u8005\u5fc5\u987b\u7531\u5bb6\u957f\u6216\u76d1\u62a4\u4eba\u966a\u540c\u5230\u672c\u4e2d\u5fc3\u8fdb\u884c\u68c0\u67e5\u3002 <\/li>\n<li>\u5982\u6709\u4efb\u4f55\u7591\u95ee\uff0c\u6b22\u8fce\u81f4\u7535 2192 7022 \u6216\u53d1\u9001\u7535\u90ae\u81f3 tmc@trinitymedical.com.hk \u67e5\u8be2\u3002 <\/li>\n<li>\u5168\u4ec1\u533b\u52a1\u4e2d\u5fc3\u4fdd\u7559\u4fee\u6539\u6761\u6b3e\u53ca\u7ec6\u5219\u4e4b\u6743\u5229\uff0c\u6055\u4e0d\u53e6\u884c\u901a\u77e5\u3002 <\/li>\n<li>\u5982\u6709\u4efb\u4f55\u4e89\u8bae\uff0c\u5168\u4ec1\u533b\u52a1\u4e2d\u5fc3\u4fdd\u7559\u6700\u7ec8\u51b3\u5b9a\u6743\u3002 <\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>\u9057\u4f20\u6027\u57fa\u56e0\u68c0\u6d4b\u4e0d\u6b62\u4e8eBRCA1 &amp; 2\uff0c\u5982\u679c\u4ec5\u68c0\u6d4bBRCA1\/2\uff0c\u53ef\u80fd\u9519\u8fc740-50%\u7684\u9057\u4f20\u6027\u764c\u75c7\u4e2a\u6848<\/p>\n<ul>\n<li dir=\"ltr\"><strong>\u5168\u9762\u8986\u76d6<\/strong>\uff1a\u68c0\u6d4b20\u4e2a\u4e0e\u9057\u4f20\u6027\u4e73\u764c\u548c\u5987\u79d1\u764c\u75c7\u76f8\u5173\u7684\u57fa\u56e0\uff0c\u63d0\u4f9b\u5168\u9762\u7684\u98ce\u9669\u8bc4\u4f30<\/li>\n<li dir=\"ltr\"><strong>\u9ad8\u7cbe\u51c6\u5ea6<\/strong>\uff1a\u91c7\u7528\u6b21\u4e16\u4ee3\u5b9a\u5e8f\u6280\u672f\uff0c\u786e\u4fdd\u68c0\u6d4b\u7ed3\u679c\u7684\u51c6\u786e\u6027\u548c\u53ef\u9760\u6027<\/li>\n<li dir=\"ltr\"><strong>\u7ec8\u8eab\u4ef7\u503c<\/strong>\uff1a\u57fa\u56e0\u8d44\u8baf\u7ec8\u751f\u4e0d\u53d8\uff0c\u4e00\u6b21\u68c0\u6d4b\u5373\u53ef\u4e3a\u60a8\u548c\u5bb6\u4eba\u63d0\u4f9b\u957f\u671f\u7684\u5065\u5eb7\u6307\u5f15<\/li>\n<\/ul>\n<p><a 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